24 September 2014 Last updated at 22:38
Brazilian researchers in Rio de Janeiro have released thousands of mosquitoes infected with bacteria that suppress dengue fever.
The hope is they will multiply, breed and become the majority of mosquitoes, thus reducing cases of the disease.
The initiative is part of a programme also taking place in Australia, Vietnam and Indonesia.
The intracellular bacteria, Wolbachia, being introduced cannot be transmitted to humans.
The programme started in 2012 says Luciano Moreira of the Brazilian research institute Fiocruz, who is leading the project in Brazil .
"Our teams performed weekly visits to the four neighbourhoods in Rio being targeted. Mosquitoes were analysed after collection in special traps.
"Transparency and proper information for the households is a priority. "
Ten thousand mosquitoes will be released each month for four months with the first release in Tubiacanga, in the north of Rio.
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