Thursday 14 June 2018

Improved ape genome assemblies provide new insights into human evolution



Better understanding of genetic influences on primate and human brain differences was also gained through comparative organoid models

Date:  June 7, 2018
Source:  University of Washington Health Sciences/UW Medicine

Summary:
Higher-quality assemblies of great ape genomes have now been generated without guidance of the human reference genome. They provide a clearer view of genetic differences that arose as humans diverged from other primates. The newest investigation offers the most comprehensive catalog of genetic variants that were gained or lost in different ape lineages. The influence of these variants was explored in brain development, dietary needs and anatomy. A fossil virus found in ape but not human genomes was also examined.


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