Thousands of goats and rabbits vanish from major biotech lab

Santa Cruz Biotechnology is one of the world’s largest antibody providers — and the subject of a US government animal-welfare investigation.

Sara Reardon

19 February 2016 Clarified: 

24 February 2016

Santa Cruz Biotechnology has used goats to make antibodies for research.

In July 2015, the major antibody provider Santa Cruz Biotechnology owned 2,471 rabbits and 3,202 goats. Now the animals have vanished, according to the US Department of Agriculture (USDA).

The company, which is headquartered in Dallas, Texas, is one of the world’s largest providers of antibodies — extracting them from animals such as goats and rabbits by injecting the animals with proteins to stimulate antibody production. Biomedical researchers can then use these antibodies to detect and label the same protein in cell or tissue samples.

But Santa Cruz Biotech is also the subject of three animal-welfare complaints filed by the USDA after its inspectors found evidence that the firm mistreated goats at its facility in California.

Santa Cruz Biotech has contested the complaints, prompting a hearing in August before a USDA administrative law judge in Washington DC. Four days into the hearing, both parties asked to suspend the proceedings in order to negotiate a settlement. But those negotiations fell through in September.

The USDA hearing is set to resume on 5 April. If Santa Cruz Biotech is found to have violated the US Animal Welfare Act, it could be fined or lose its licence to keep animals for commercial use. The USDA says that the company could face a maximum fine of US$10,000 per violation for each day that a given violation persists. The agency has reported 31 alleged violations by the company.

Disappearing act

In the meantime, the company seems to have done away with its entire animal inventory. When the USDA inspected the firm's California facility on 12 January, it found no animal-welfare violations, and listed “no animals present or none inspected”. USDA spokesman Ed Curlett says that no animals were present during the inspection.

The fate of the goats and rabbits is unclear. The company did not respond to questions about the matter, and David Schaefer, director of public relations for the law firm Covington & Burling in Washington DC, which is representing Santa Cruz Biotechnology, declined to comment on the animals’ fate.

As research animals, the goats and rabbits could not be sold for meat, although they could be sold to another business or research entity. Cathy Liss, president of the Animal Welfare Institute, an advocacy group in Washington DC, suspects that the animals were killed. She says that it is unlikely that such a large number of animals bred for such a specific purpose would find a buyer.

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