Four Natural Extracts With Anti-Obesity Effects Tested On Rats

ScienceDaily (Feb. 10, 2012) — University of Granada researchers have identified four plant extracts that might help in preventing and fighting obesity. The researchers identified the most effective plant extracts through in vitro assays; subsequently, extracts were tested on rats. While the results obtained are promising, further studies on animals are required to evaluate and confirm the anti-obesity effects of these extracts. Once their anti-obesity effects are confirmed on animals, the extracts will be tested on humans.

In vitro assays revealed that two of these extracts -which name cannot be disclosed for confidentiality reasons- inhibited the activity of one of the key enzymes involved in the breakdown of dietary lipids, which would eventually reduce lipid absorption.

In addition, cell assays revealed that another two extracts induced the hydrolysis ​​of the triglycerides accumulated within fat cells, thus reducing their fat content.

Tested on Rats

The effects of these extracts were tested on animals. To carry out this study, Wistar rats were used as a model for study of the absorption of a fat-rich diet, and Zucker rats -characterized for being obese rats- were used as a model for studying the effects of these extracts on body weight and plasma lipid levels in obese animals.

Read on:  http://www.sciencedaily.com/releases/2012/02/120210110036.htm