Monday 15 October 2012

Spotting a Trend in the Genes: Three Genes That Cause Cancer and Disease in Humans Also 'Paint' Spots On Butts of Fruit Flies


ScienceDaily (Oct. 12, 2012) — Spots on the butts of fruit flies are really, really small. But what a researcher and his graduate student are discovering about them could be gigantic.

Thomas Werner, assistant professor of biological sciences at Michigan Technological University, and his PhD student, Komal Kumar Bollepogu Raja, have discovered that three genes that cause cancer and disease in humans also "paint" the spots on the fly's body. This discovery could enable researchers to study how those genes work in fruit flies and apply that knowledge to treating cancer in people.

"The last common ancestor of man and fruit flies lived about 600 million years ago," says Werner. "All the genes needed to build a body were already present in that ancestor, and today we still share virtually all of our body-building genes with fruit flies. This is why we are able to study human diseases like cancer in fruit flies."

Werner and Raja are interested in how DNA encodes body forms and patterns in animals. They use color patterns as a model.


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