The world's
first brain-to-brain connection has given rats the power to communicate by
thought alone.
"Many
people thought it could never happen," says Miguel Nicolelis at Duke University
in Durham , North Carolina . Although monkeys
have been able to control robots with their mind using
brain-to-machine interfaces, work by Nicolelis's team has, for the first time,
demonstrated a direct interface between two brains – with the rats able to
share both motor and sensory information.
The feat was
achieved by first training rats to press one of two levers when an LED above
that lever was lit. A correct action opened a hatch containing a drink of
water. The rats were then split into two groups, designated as
"encoders" and "decoders".
An array of
microelectrodes – each about one-hundredth the width of a human hair – was then
implanted in the encoder rats' primary motor cortex, an area of the brain that
processes movement. The team used the implant to record the neuronal activity
that occurs just before the rat made a decision in the lever task. They found
that pressing the left lever produced a different pattern of activity from
pressing the right lever, regardless of which was the correct action.
Next, the team
recreated these patterns in decoder rats, using an implant in the same brain
area that stimulates neurons rather than recording from them. The decoders
received a few training sessions to prime them to pick the correct lever in
response to the different patterns of stimulation.
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